drugset / Trial / NCT04350190
Apatinib Combined With PD-1 in the Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma
Phase 2
Completed
25 enrolled
Wei Jiang
Guangxi Naxishan Hospital · collabLaibin People's Hospital · collabPeople's Hospital of Lingshan · collabWuzhou Red Cross Hospital · collab
NaSingle-groupOpen-labelTreatment
Summary
The study is to evaluate the clinical efficacy of apatinib mesylate tablets combined with PD-1 in the treatment of recurrent and metastatic nasopharyngeal carcinoma after IMRT with concurrent chemotherapy,including The Overall Response Rate (ORR), Progression-free survival (PFS),Overall survival (OS),and Toxicities.
Timeline
- Start
- 2021-01-14
- Primary completion
- 2022-09-15
- Completion
- 2022-09-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Camrelizumab | Monoclonal antibody | 200 mg | Intravenous |
| Subject | Rivoceranib | Small molecule | 250 mg | Oral |