Intra Articular Injection of Microfat and PRP in Knee Osteoarthritis

NCT04352075 ↗

Phase 1/2 Completed 30 enrolled Clinique Juge

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The hypothesis of this project is that the injection of an innovative treatment (microfat and dose of autologous PRP) allows to delay knee arthroplasty in patients with knee OA resistant to medical treatment.

Timeline

Start: 2018-11-15
Primary completion: 2019-08-01
Completion: 2020-03-01

Publications

Louis ML, Dumonceau RG, Jouve E, Cohen M, Djouri R, Richardet N, Jourdan E, Giraudo L, Dumoulin C, Grimaud F, George FD, Veran J, Sabatier F, Magalon J. Intra-Articular Injection of Autologous Microfat and Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis: A Double-Blind Randomized Comparative Study. Arthroscopy. 2021 Oct;37(10):3125-3137.e3. doi: 10.1016/j.arthro.2021.03.074. Epub 2021 Apr 20.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Autologous biologic drug of innovative therapy /cell therapy drug	Unknown	5 ml	Other
Subject	Platelet Rich Plasma	Other / unclassified	5 ml	Other
Subject	Platelet Rich Plasma	Other / unclassified	1e+09 cells	Other
Subject	Platelet Rich Plasma	Other / unclassified	3e+09 cells	Other

Intra Articular Injection of Microfat and PRP in Knee Osteoarthritis

Summary

Timeline

Publications

Drugs

Indications