drugset / Trial / NCT04353661

A Study Of ¹²⁹XE MRI To Assess Disease Progression In Patients With COPD Treated With Or Without Azithromycin And Standard-of-Care Medications

NCT04353661

Phase 2 Terminated 12 enrolled Genentech, Inc.
RandomizedParallel-groupOpen-labelTreatment

Summary

This study will test whether daily use of azithromycin will reduce the rate of exacerbations and improve lung ventilation and perfusion assessed by XE-MRI. The sensitivity of XE-MRI to detect COPD progression will be compared with standard clinical assessment measures including standard lung function tests, 6 minute walk test, and patient reported quality of life.

Timeline

Start
2021-11-16
Primary completion
2023-06-29
Completion
2023-06-29

Drugs

EvaluationDrugModalityDoseRoute
Subject Azithromycin Small molecule Oral