drugset / Trial / NCT04357028

Measles Vaccine in HCW

NCT04357028

Phase 3 Suspended 200 enrolled Kasr El Aini Hospital
RandomizedParallel-groupSingle-blindPrevention

Summary

Till now, mortality reports among children below 9 years remains extremely low despite that the incidence of death toll is high and exceeding 50,000 patients among older population, One speculation for lower SARS infectivity is that cross-protective antibodies against measles vaccine ( MV). In mice susceptible to measles virus, recombinant MV induced the highest titers of neutralizing antibodies and fully protected immunized animals from intranasal infectious challenge with SARS-CoV, The primary objective of the present study is to determine the benefit of measles vaccine in health care professional to decrease the incidence of COVID-19. We Hypothesized that, measles vaccine may lower the incidence of serologically proven SARS-CoV-2 infection and reported respiratory illness

Timeline

Start
2020-07-13
Primary completion
2020-12-31
Completion
2021-01-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Measles-Mumps-Rubella Vaccine Vaccine 0.5 ml Subcutaneous

Indications