drugset / Trial / NCT04358523
A Study of the Relative Bioavailability of ASC18 Tablets vs Reference Tablets in Healthy Volunteers
RandomizedCrossoverOpen-labelTreatment
Summary
The objective of this study is to evaluate potential drug interaction between RDV and SOF in ASC18 tablets (RDV/SOF compound tablets) and the influence of food effect on the pharmacokinetics of ASC18 tablets were evaluated in healthy subjects -and compare the pharmacokinetic parameters of ASC18 tablets（ravidasvir and sofosbuvir fixed dose combination）with ravidasvir tablets and sofosbuvir tablets in healthy subjects after single and multiple oral dosing.
Timeline
- Start
- 2020-03-20
- Primary completion
- 2020-12-15
- Completion
- 2020-12-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ravidasvir | Small molecule | 200 mg | Oral |
| Subject | Sofosbuvir | Small molecule | 400 mg | Oral |
Indications
No indication recorded.