drugset / Trial / NCT04361643

Low-dose Lenalidomide for Non-severe COVID-19 Treatment Trial

NCT04361643

Phase 4 Unknown 120 enrolled Hospital Universitario Getafe
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Double-blind randomized controlled clinical trial (RCT) of low-dose lenalidomide in the treatment of elderly patients (\> 60 years of age) with mild to moderate clinical signs of COVID-19 disease from the Hospital Universitario of Getafe. The study will include patients of both sexes (\> 60 years of age) with mild to moderate clinical presentation of COVID-19 (ROX index \> 10). Subjects will be randomly assigned to the experimental arm with lenalidomide (5 mg/24h, day 1, 3 and 5) or to the controlled arm. Other concomitant medication for the treatment of COVID-19 will be also considered.

Timeline

Start
2020-10-27
Primary completion
2021-08-31
Completion
2021-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Lenalidomide Other / unclassified 5 mg Oral

Indications