drugset / Trial / NCT04365153
Canakinumab in Covid-19 Cardiac Injury (The Three C Study)
RandomizedParallel-groupQuadruple-blindTreatment
Summary
TThe purpose of this prospective, Phase 2, single center, blinded, randomized controlled study is to demonstrate as a proof of concept that early treatment with canakinumab prevents progressive heart and respiratory failure in patients with COVID-19 infection. These results will lead to and inform a Phase III randomized placebo-controlled trial.
Timeline
- Start
- 2020-04-24
- Primary completion
- 2021-02-02
- Completion
- 2021-04-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Canakinumab | Monoclonal antibody | 300 mg | Intravenous |
| Comparator | Canakinumab | Monoclonal antibody | 600 mg | Intravenous |