drugset / Trial / NCT04367909

A Study of TC(Docetaxel and Carboplatin) Regimen With or Without Nimotuzumab in Recurrent Metastatic Oral Squamous Cell Carcinoma

NCT04367909

Phase 2 Unknown 68 enrolled Xin-Hua Xu
RandomizedParallel-groupOpen-labelTreatment

Summary

This prospective, single-center, randomized, controlled study will evaluate the efficacy and safety of TC Regimenwith or without nimotuzumab in recurrent metastatic oral squamous cell carcinoma. Treatment may continue as long as participants are experiencing clinical benefit as assessed by the investigator, i.e., in the absence of unacceptable toxicity or symptomatic deterioration attributed to disease progression.

Timeline

Start
2020-06-21
Primary completion
2021-12-01
Completion
2022-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Nimotuzumab Monoclonal antibody 200 mg Intravenous
Background Carboplatin Small molecule Intravenous
Background Docetaxel Small molecule 75 mg/m2 Intravenous