drugset / Trial / NCT04374136

A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

NCT04374136

Phase 3 Terminated 119 enrolled Alector Inc. GlaxoSmithKline · collab
RandomizedParallel-groupQuadruple-blindTreatment

Summary

A phase 3 double blind, placebo controlled study evaluating the efficacy and safety of AL001 in participants at risk for or with frontotemporal dementia due to heterozygous mutations in the progranulin gene.

Timeline

Start
2020-07-23
Primary completion
2025-09-01
Completion
2026-01-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Latozinemab Monoclonal antibody Intravenous