drugset / Trial / NCT04376281
The Effect of Norepinephrine on Cardiac Output in Patients Undergoing Liver Transplant .
NaSingle-groupOpen-labelTreatment
Summary
Early administration of NE in liver transplant recipient might enhance cardiac output through an increase in cardiac preload .
Timeline
- Start
- 2019-12-15
- Primary completion
- 2021-08-01
- Completion
- 2021-10-01
Publications
- Background Rudnick MR, Marchi LD, Plotkin JS. Hemodynamic monitoring during liver transplantation: A state of the art review. World J Hepatol. 2015 Jun 8;7(10):1302-11. doi: 10.4254/wjh.v7.i10.1302.
- Background Moller S, Bendtsen F, Henriksen JH. Effect of volume expansion on systemic hemodynamics and central and arterial blood volume in cirrhosis. Gastroenterology. 1995 Dec;109(6):1917-25. doi: 10.1016/0016-5085(95)90759-9.
- Background Mukhtar A, Dabbous H. Modulation of splanchnic circulation: Role in perioperative management of liver transplant patients. World J Gastroenterol. 2016 Jan 28;22(4):1582-92. doi: 10.3748/wjg.v22.i4.1582.
- Background Maas JJ, Geerts BF, van den Berg PC, Pinsky MR, Jansen JR. Assessment of venous return curve and mean systemic filling pressure in postoperative cardiac surgery patients. Crit Care Med. 2009 Mar;37(3):912-8. doi: 10.1097/CCM.0b013e3181961481.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Noradrenaline | Unknown | — | — |
Indications
No indication recorded.