drugset / Trial / NCT04387825

Safety Of Fat Micrografts With Adipose-Derived Stromal Vascular Fraction In Hands Of Patients With Systemic Sclerosis

NCT04387825 ↗

RandomizedParallel-groupOpen-labelTreatment

Summary

Systemic sclerosis (SS) causes microvascular alteration in the hand and subsequently pain, skin fibrosis, and osteoarticular deformities. These injuries initiate functional decline of the hand and decrease patient quality of life. Local application of adipose-derived stromal vascular fraction (ADSVF) has been proposed as an emerging treatment. There are reports about the good results obtained after ADSVF treatment in this kind of patients. For these reasons , we aimed to evaluate the safety and clinical effect of application of fat micrografts enriched with ADSVF to the hands of patients with SS.

Timeline

Start
2015-08-13
Primary completion
2019-05
Completion
2020-05

Drugs

EvaluationDrugModalityDoseRoute
Subject ADSVF Cell therapy 2 ml Subcutaneous

Indications