drugset / Trial / NCT04387825
Safety Of Fat Micrografts With Adipose-Derived Stromal Vascular Fraction In Hands Of Patients With Systemic Sclerosis
Phase 2
Completed
20 enrolled
National Institute of Medical Sciences and Nutrition Salvador Zubiran
National Council of Science and Technology, Mexico · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
Systemic sclerosis (SS) causes microvascular alteration in the hand and subsequently pain, skin fibrosis, and osteoarticular deformities. These injuries initiate functional decline of the hand and decrease patient quality of life. Local application of adipose-derived stromal vascular fraction (ADSVF) has been proposed as an emerging treatment. There are reports about the good results obtained after ADSVF treatment in this kind of patients. For these reasons , we aimed to evaluate the safety and clinical effect of application of fat micrografts enriched with ADSVF to the hands of patients with SS.
Timeline
- Start
- 2015-08-13
- Primary completion
- 2019-05
- Completion
- 2020-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ADSVF | Cell therapy | 2 ml | Subcutaneous |