drugset / Trial / NCT04389450

Double-Blind, Multicenter, Study to Evaluate the Efficacy of PLX PAD for the Treatment of COVID-19

NCT04389450 ↗

Phase 2 Terminated 66 enrolled Pluristem Ltd.
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This clinical trial will examine if a new treatment of Mesenchymal-like Adherent stromal Cells (called PLX-PAD) can help patients intubated and mechanically ventilated due to COVID-19 to recover more quickly with less complications.

Timeline

Start
2020-10-01
Primary completion
2021-05-17
Completion
2023-06-07

Outcome

Outcome not reported

Stopped: “The decision to bring the Study to early clinical readout came in response to COVID-19's evolution as a disease, and the significant changes in the standard of care, leading to an increase in the severity of conditions of the intubated patients”

Drugs

EvaluationDrugModalityDoseRoute
Subject EMIPLACEL Cell therapy 1 ml Intramuscular
Subject EMIPLACEL Cell therapy 300 unknown Intramuscular