drugset / Trial / NCT04393493

The Effect in Renal Function on Patients With Type 1 Cardiorenal Syndrome Treated With Two Strategies of Furosemide.

NCT04393493 ↗

Phase 2 Completed 80 enrolled Hospital Civil de Guadalajara
RandomizedParallel-groupDouble-blindTreatment

Summary

In double-blind clinical trial, determine renal recovery with two different furosemide strategies in patients with type 1 cardiorenal syndrome.

Timeline

Start
2017-07-01
Primary completion
2020-04-01
Completion
2020-04-01

Outcome

Missed primary endpoint

paper The primary endpoint occurred in 20% of the SF group and 15.2% of the DC group (p = 0.49). PMID 34979962 ↗

Drugs

EvaluationDrugModalityDoseRoute
Subject Chlortalidone Unknown 50 mg Oral
Subject Furosemide Other / unclassified 80 mg Intravenous
Subject Furosemide Other / unclassified 100 mg Intravenous
Subject Furosemide Other / unclassified 400 mg Intravenous
Subject Spironolactone Small molecule 50 mg Oral

Indications