drugset / Trial / NCT04393753

Domatinostat in Combination With Avelumab in Patients With Advanced Merkel Cell Carcinoma Progressing on Anti-PD-(L)1

NCT04393753 ↗

Phase 2 Completed 19 enrolled 4SC AG
NaSingle-groupOpen-labelTreatment

Summary

This phase II trial studies how well domatinostat (4SC-202) works in combination with avelumab in adult patients with advanced unresectable and/or metastatic Merkel Cell Carcinoma that have progressed on a previous therapy with an anti-PD-(L)1 antibody

Timeline

Start
2020-10-13
Primary completion
2024-02-26
Completion
2024-02-26

Drugs

EvaluationDrugModalityDoseRoute
Subject Avelumab Monoclonal antibody — —
Subject Domatinostat Small molecule — —