Analgesic Efficacy of Continuous Infusion of Local Anaesthetic Versus Single-shot Injection Interscalene Block

Summary

The aim of this study is to study the analgesic efficacy of a continuous infusion of local anaesthetics for interscalene brachial plexus block after major shoulder surgery in the setting of multimodal analgesia, in order to determine whether the use of a catheter is still necessary in a contemporary practice.

Timeline

Start

2020-05-12

Primary completion

2022-08-31

Completion

2022-09-30

Outcome

Missed primary endpoint

paper 10 mg (4-24) in the continuous infusion group and 14 mg (8-26) in the single injection group (p=0.74). PMID 37541683 ↗

paper A continuous infusion of local anesthetic for an interscalene brachial plexus block does not provide superior analgesia PMID 37541683 ↗

Publications

• Rhyner P, Cachemaille M, Goetti P, Rossel JB, Boand M, Farron A, Albrecht E. Single-bolus injection of local anesthetic, with or without continuous infusion, for interscalene brachial plexus block in the setting of multimodal analgesia: a randomized controlled unblinded trial. Reg Anesth Pain Med. 2024 May 7;49(5):313-319. doi: 10.1136/rapm-2023-104681.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ropivacaine	Other / unclassified	0.2 %	Other

Indications

No indication recorded.