drugset / Trial / NCT04403568
Testing the Synergism of Phytonutrients, Curcumin and Ursolic Acid, to Target Molecular Pathways in the Prostate
Non-randomizedSequentialOpen-labelBasic science
Summary
A proof of concept clinical trial to assess the synergism of curcumin (CURC) and ursolic acid (UA). Before further testing within formal cancer clinical trials, we must (1) evaluate the bioavailability and safety, (2) confirm the presence of metabolites in the target organ, and (3) validate the appropriate mechanism of effect
Timeline
- Start
- 2021-10
- Primary completion
- 2022-12
- Completion
- 2023-12
Outcome
Outcome not reported
Stopped (Enrollment): “No subjects were enrolled in this study, the PI will seek funding and revise the protocol for resubmisson at a later date”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Curcumin | Small molecule | 600 mg | — |
| Subject | Ursolic Acid | Small molecule | 150 mg | — |