drugset / Trial / NCT04403568

Testing the Synergism of Phytonutrients, Curcumin and Ursolic Acid, to Target Molecular Pathways in the Prostate

NCT04403568 ↗

Non-randomizedSequentialOpen-labelBasic science

Summary

A proof of concept clinical trial to assess the synergism of curcumin (CURC) and ursolic acid (UA). Before further testing within formal cancer clinical trials, we must (1) evaluate the bioavailability and safety, (2) confirm the presence of metabolites in the target organ, and (3) validate the appropriate mechanism of effect

Timeline

Start
2021-10
Primary completion
2022-12
Completion
2023-12

Outcome

Outcome not reported

Stopped (Enrollment): “No subjects were enrolled in this study, the PI will seek funding and revise the protocol for resubmisson at a later date”

Drugs

EvaluationDrugModalityDoseRoute
Subject Curcumin Small molecule 600 mg —
Subject Ursolic Acid Small molecule 150 mg —

Indications