drugset / Trial / NCT04406272

VB-111 in Surgically Accessible Recurrent/Progressive GBM

NCT04406272 ↗

RandomizedParallel-groupDouble-blindTreatment

Summary

This research study is studying a new viral cancer therapy, ofranergene obadenovec (VB-111), for recurrent or progressive glioblastoma (GBM), a brain tumor that is growing or progressing despite earlier treatment.

Timeline

Start
2020-08-01
Primary completion
2024-08-01
Completion
2024-08-01

Outcome

Outcome not reported

Stopped: “Trial stopped at request of VBL Therapeutics, as they are no longer pursuing their VB-111 development program.”

Drugs

EvaluationDrugModalityDoseRoute
Subject VB11 Unknown — Intravenous
Background Bevacizumab Monoclonal antibody — Intravenous

Indications