drugset / Trial / NCT04406272
VB-111 in Surgically Accessible Recurrent/Progressive GBM
Phase 2
Terminated
15 enrolled
Dana-Farber Cancer Institute
Vascular Biogenics Ltd. operating as VBL Therapeutics · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
This research study is studying a new viral cancer therapy, ofranergene obadenovec (VB-111), for recurrent or progressive glioblastoma (GBM), a brain tumor that is growing or progressing despite earlier treatment.
Timeline
- Start
- 2020-08-01
- Primary completion
- 2024-08-01
- Completion
- 2024-08-01
Outcome
Outcome not reported
Stopped: “Trial stopped at request of VBL Therapeutics, as they are no longer pursuing their VB-111 development program.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | VB11 | Unknown | — | Intravenous |
| Background | Bevacizumab | Monoclonal antibody | — | Intravenous |