drugset / Trial / NCT04410094
A Study to Assess the Effects of Itraconazole and Rifampin on Lazertinib in Healthy Adult Participants
Non-randomizedParallel-groupOpen-labelOther
Summary
The purpose of this study is to evaluate the effects of multiple doses of strong cytochrome P450 (CYP) 3A4 inhibitor itraconazole and strong CYP3A4 inducer rifampin on the single dose pharmacokinetics (PK) of lazertinib in healthy adult participants.
Timeline
- Start
- 2020-09-14
- Primary completion
- 2020-12-30
- Completion
- 2021-02-02
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Itraconazole | Small molecule | — | Oral |
| Subject | Lazertinib | Small molecule | — | Oral |
| Subject | Rifampin | Small molecule | — | Oral |
Indications
No indication recorded.