drugset / Trial / NCT04417088

Exablate Blood-Brain Barrier Disruption for the Treatment of rGBM in Subjects Undergoing Carboplatin Monotherapy

NCT04417088 ↗

Phase 1/2 Completed 28 enrolled InSightec
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety and feasibility of the Exablate Model 4000 Type 2 system when used as a tool to open the blood-brain-barrier (BBB) in subjects with recurrent glioblastoma (rGBM) undergoing carboplatin monotherapy.

Timeline

Start
2020-11-06
Primary completion
2023-11-30
Completion
2023-12-31

Drugs

EvaluationDrugModalityDoseRoute
Background Carboplatin Small molecule — Intravenous

Indications