drugset / Trial / NCT04417764
TACE Combined With PD-1 Knockout Engineered T Cell in Advanced Hepatocellular Carcinoma.
NaSingle-groupOpen-labelTreatment
Summary
This study will evaluate the safety and effect of transcatheter arterial chemoembolization (TACE)combined with percutaneous transhepatic PD-1 knockout engineered T cell infusion in the Paitents with advanced hepatocellular carcinoma(HCC). Blood and tissue samples will also be collected for research purposes.
Timeline
- Start
- 2019-06-20
- Primary completion
- 2024-12-30
- Completion
- 2024-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | PD-1 knockout Engineered T cells | Cell therapy | 1e+09 cells | Other |
| Subject | PD-1 knockout Engineered T cells | Cell therapy | 3e+09 cells | Other |