drugset / Trial / NCT04430595

Multi-4SCAR-T Therapy Targeting Breast Cancer

NCT04430595 ↗

Phase 1/2 Recruiting 100 enrolled Shenzhen Geno-Immune Medical Institute
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to assess the feasibility, safety and efficacy of multiple 4th generation CAR-T cells targeting Her2, GD2, and CD44v6 surface antigen in breast cancer. Another goal of the study is to learn more about the activities of the multi-CAR T cells and their persistency in the patients.

Timeline

Start
2026-06-01
Primary completion
2029-12-31
Completion
2030-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject 4SCAR-CD44v6 Cell therapy — Other
Subject 4SCAR-GD2 Cell therapy — Other
Subject 4SCAR-Her2 Cell therapy — Other

Indications