drugset / Trial / NCT04433221

Combination Immunotherapy Targeting Sarcomas

NCT04433221 ↗

Phase 1/2 Recruiting 20 enrolled Shenzhen Geno-Immune Medical Institute
NaSingle-groupOpen-labelTreatment

Summary

The aim of this clinical trial is to assess the feasibility, safety and efficacy of a combination low dose chemotherapy and immunotherapy in patients who have sarcoma that is relapsed or late staged. Another goal of the study is to assess the safety and efficacy of the therapy that combines multiple CAR T cells followed by sarcoma vaccines.

Timeline

Start
2026-07-01
Primary completion
2029-05-31
Completion
2029-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Multiple sarcoma-specific CAR-T cells Cell therapy 1e+06 cells/kg Intravenous
Subject Multiple sarcoma-specific CAR-T cells Cell therapy 1e+07 cells/kg Intravenous