drugset / Trial / NCT04435977

Efficacy and Safety of Cabozantinib in Patients With Hepatocellular Carcinoma

NCT04435977 ↗

Phase 2 Unknown 46 enrolled Istituto Clinico Humanitas
NaSingle-groupOpen-labelTreatment

Summary

This is an open-label, single-center, Phase II trial designed to estimate in terms of PFS the efficacy of cabozantinib, given as second- or third- line treatment in HCC patients that progress on or are intolerant to immune checkpoint inhibitors, including anti-PD-1 and anti-PD-L1 antibodies.

Timeline

Start
2020-01-30
Primary completion
2023-06
Completion
2023-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Cabozantinib Small molecule 60 mg Oral