drugset / Trial / NCT04437329
Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma
Phase 3
Recruiting
352 enrolled
Affiliated Cancer Hospital & Institute of Guangzhou Medical University
RandomizedParallel-groupOpen-labelTreatment
Summary
To compare the effectiveness and toxicity of nedaplatin versus cisplatin in induction chemotherapy combined with concurrent chemoradiotherapy for locoregionally advanced nasopharyngeal carcinoma.
Timeline
- Start
- 2020-08-01
- Primary completion
- 2028-06-30
- Completion
- 2029-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cisplatin | Other / unclassified | 60 mg/m2 | Intravenous |
| Comparator | Cisplatin | Other / unclassified | 100 mg/m2 | Intravenous |
| Subject | Nedaplatin | Small molecule | 60 mg/m2 | Intravenous |
| Subject | Nedaplatin | Small molecule | 100 mg/m2 | Intravenous |
| Background | Docetaxel | Small molecule | 60 mg/m2 | Intravenous |
| Background | fluorouracil | Small molecule | 3000 mg/m2 | Intravenous |