drugset / Trial / NCT04437810

To Study Efficacy of Albumin in Cirrhosis With Spontaneous Bacterial Peritonitis at Low Risk for AKI Development

NCT04437810

RandomizedParallel-groupDouble-blindTreatment

Summary

The role of Albumin in prevention and Treatment of Acute Kidney Injury (AKI) in patients with Spontaneous Bacterial Peritonitis (SBP) who are at high risk of AKI development has been clearly defined , which decreases the morbidity and mortality. But the role of Albumin in patient with SBP who are at low risk of AKI development (Serum Bilirubin \<4mg/dl, Creatinine \<1mg/dl at the time of presentation) has been controversial and there are no placebo controlled trials. We propose that Albumin at the standard doses is beneficial in preventing development of AKI in patients with SBP who are at low risk of AKI development.

Timeline

Start
2020-07-08
Primary completion
2022-04-30
Completion
2022-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Albumin Protein / enzyme biologic 1 g/kg