drugset / Trial / NCT04439006

Ibrutinib for the Treatment of COVID-19 in Patients Requiring Hospitalization

NCT04439006

RandomizedParallel-groupOpen-labelTreatment

Summary

This phase Ib/II trial studies the side effects and best dose of ibrutinib and how well it works in treating patients with COVID-19 requiring hospitalization. Ibrutinib may help improve COVID-19 symptoms by lessening the inflammatory response in the lungs, while preserving overall immune function. This may reduce the need to be on a ventilator to help with breathing.

Timeline

Start
2020-10-23
Primary completion
2022-09-20
Completion
2022-09-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Ibrutinib Small molecule Oral