drugset / Trial / NCT04439175

Testing GDC-0032 (Taselisib) as a Potential Targeted Treatment in Cancers With PIK3CA Genetic Changes (MATCH-Subprotocol I)

NCT04439175

Phase 2 Active not recruiting 70 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase II MATCH treatment trial identifies the effects of GDC-0032 (taselisib) in patients whose cancer has a genetic change called PIK3CA mutation. Taselisib may stop the growth of cancer cells by blocking PIK3CA, a protein that may be needed for cell growth. Researchers hope to learn if taselisib will shrink this type of cancer or stop its growth.

Timeline

Start
2016-02-25
Primary completion
2020-11-10
Completion
2027-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Taselisib Small molecule 4 mg Oral