drugset / Trial / NCT04440358

Exablate Blood-Brain Barrier Disruption With Carboplatin for the Treatment of rGBM

NCT04440358 ↗

Phase 1/2 Completed 13 enrolled InSightec
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety and feasibility of the Exablate Model 4000 Type 2 system when used as a tool to open the blood-brain-barrier (BBB) in subjects with recurrent glioblastoma (rGBM) undergoing carboplatin monotherapy.

Timeline

Start
2020-10-13
Primary completion
2023-11-30
Completion
2023-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule — Intravenous

Indications