drugset / Trial / NCT04440774

Research Study to Assess New Chikungunya and Zika Vaccines in Healthy Adults in Mexico.

NCT04440774 ↗

Phase 1 Completed 120 enrolled University of Oxford
RandomizedSequentialDouble-blindPrevention

Summary

Phase Ib, single centre, double-blind, double-dummy placebo-controlled, randomised, stepwise dose escalated, vaccine trial to assess the safety and immunogenicity of the candidate ChAdOx1 Chik and ChAdOx1 Zika vaccines, given as a standalone vaccines or in co-administration. Healthy volunteers aged 18-50 years old, residents of the metropolitan area of Monterrey (Mexico), will be recruited as participants

Timeline

Start
2020-10-23
Primary completion
2022-02-18
Completion
2022-02-18

Drugs

EvaluationDrugModalityDoseRoute
Subject ChAdOx1 Chik Vaccine 5e+09 unknown Intramuscular
Subject ChAdOx1 Chik Vaccine 2.5e+10 unknown Intramuscular
Subject ChAdOx1 Chik Vaccine 5e+10 unknown Intramuscular
Subject ChAdOx1 Zika Vaccine 5e+09 unknown Intramuscular
Subject ChAdOx1 Zika Vaccine 2.5e+10 unknown Intramuscular
Subject ChAdOx1 Zika Vaccine 5e+10 unknown Intramuscular