drugset / Trial / NCT04440774
Research Study to Assess New Chikungunya and Zika Vaccines in Healthy Adults in Mexico.
RandomizedSequentialDouble-blindPrevention
Summary
Phase Ib, single centre, double-blind, double-dummy placebo-controlled, randomised, stepwise dose escalated, vaccine trial to assess the safety and immunogenicity of the candidate ChAdOx1 Chik and ChAdOx1 Zika vaccines, given as a standalone vaccines or in co-administration. Healthy volunteers aged 18-50 years old, residents of the metropolitan area of Monterrey (Mexico), will be recruited as participants
Timeline
- Start
- 2020-10-23
- Primary completion
- 2022-02-18
- Completion
- 2022-02-18
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | ChAdOx1 Chik | Vaccine | 5e+09 unknown | Intramuscular |
| Subject | ChAdOx1 Chik | Vaccine | 2.5e+10 unknown | Intramuscular |
| Subject | ChAdOx1 Chik | Vaccine | 5e+10 unknown | Intramuscular |
| Subject | ChAdOx1 Zika | Vaccine | 5e+09 unknown | Intramuscular |
| Subject | ChAdOx1 Zika | Vaccine | 2.5e+10 unknown | Intramuscular |
| Subject | ChAdOx1 Zika | Vaccine | 5e+10 unknown | Intramuscular |