drugset / Trial / NCT04440917

Camrelizumab Combined With Apatinib Mesylate for Head and Neck Squamous Cell Carcinoma

NCT04440917 ↗

NaSingle-groupOpen-labelTreatment

Summary

This is a prospective, open-labelled study to evaluate the efficacy and safety of camrelizumab combined with apatinib mesylate in the induction treatment of patients with locally advanced head and neck squamous cell carcinoma who were judged surgically unresectable or appropriate for non-surgical definitive therapy. The objective response rate (ORR) and safety will be evaluated as the primary endpoints, the 2-year overall survival (OS) rate and progression free survival (PFS) rate will be the second endpoints.

Timeline

Start
2020-06-03
Primary completion
2022-06
Completion
2023-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Camrelizumab Monoclonal antibody 200 mg Intravenous
Subject Rivoceranib Small molecule 250 mg Oral