drugset / Trial / NCT04444349
Protective Effect of CoQ10 Against Negative Inflammatory Response and Organ Dysfunction in Cardiovascular Surgery (PANDA V)
Recruiting
500 enrolled
Nanjing Medical University
Beijing Anzhen Hospital · collabThe First Affiliated Hospital of Guangzhou Medical University · collabThe First Affiliated Hospital with Nanjing Medical University · collabWest China Hospital · collab
RandomizedParallel-groupTriple-blindPrevention
Summary
Cardiovascular diseases are the leading causes of death and prescription drug use. Research on certain dietary supplements looks promising as a way to help reduce risk factors. Previous studies showed that CoQ10 levels were decreased in cardiovascular patients and worsening of mitochondrial dysfunction was observed. The overall objective of this study is to determine if supplementing with CoQ10 can reduce inflammatory risk factors in adults with cardiac surgery, independent of other dietary or physical activity changes.
Timeline
- Start
- 2021-02-01
- Primary completion
- 2025-12-31
- Completion
- 2025-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Coenzyme Q10 | Other / unclassified | 10 mg | — |