drugset / Trial / NCT04444492
Combination of Ranibizumab and Targeted Laser Photocoagulation
RandomizedParallel-groupSingle-blindTreatment
Summary
Intravitreal injections of Ranibizumab will be applied in all patients according to treatment guidelines. The experimental group will receive additional targeted laser photocoagulation of the peripheral areas of capillary non-perfusion (up to 4 laser treatments within 1st year of the study). Based on the long-term observation after CoRaLa I study an importantly shorter duration of treatment and a relevant reduction of the total number of re-injections in RL patients is expected.
Timeline
- Start
- 2020-08-25
- Primary completion
- 2027-11-30
- Completion
- 2027-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Ranibizumab | Monoclonal antibody | — | Intravitreal |