drugset / Trial / NCT04444492

Combination of Ranibizumab and Targeted Laser Photocoagulation

NCT04444492

Phase 3 Active not recruiting 88 enrolled University of Giessen University of Leipzig · collab
RandomizedParallel-groupSingle-blindTreatment

Summary

Intravitreal injections of Ranibizumab will be applied in all patients according to treatment guidelines. The experimental group will receive additional targeted laser photocoagulation of the peripheral areas of capillary non-perfusion (up to 4 laser treatments within 1st year of the study). Based on the long-term observation after CoRaLa I study an importantly shorter duration of treatment and a relevant reduction of the total number of re-injections in RL patients is expected.

Timeline

Start
2020-08-25
Primary completion
2027-11-30
Completion
2027-11-30

Drugs

EvaluationDrugModalityDoseRoute
Background Ranibizumab Monoclonal antibody Intravitreal