drugset / Trial / NCT04445948
Lactoferrin in Helicobacter Pylori Eradication Either With Standard Triple Therapy or Sequential Therapy
RandomizedParallel-groupOpen-labelTreatment
Summary
The investigators aim at evaluating the efficacy of bovine lactoferrin addition to H. Pylori eradication regimens. 400 randomly distributed participants will be assigned to one of four treatment regimens of H. Pylori (standard triple therapy, standard triple therapy plus bovine lactoferrin, sequential therapy, or sequential therapy plus bovine lactoferrin), and eradication rates will be evaluated among the four groups.
Timeline
- Start
- 2019-11-30
- Primary completion
- 2020-06-21
- Completion
- 2020-06-21
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Amoxicillin | Other / unclassified | 1000 mg | — |
| Comparator | Clarithromycin | Small molecule | 500 mg | — |
| Comparator | Esomeprazole | Small molecule | 40 mg | Oral |
| Comparator | Lactoferrin Bovine | Protein / enzyme biologic | 200 mg | — |
| Comparator | Metronidazole | Small molecule | 500 mg | Oral |