drugset / Trial / NCT04450836
Sequences Of REGorafenib And Trifluridine/Tipiracil in Patients With Metastatic Colorectal Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
A randomized, phase II study comparing the sequences of regorafenib and trifluridine/tipiracil, after failure of standard therapies in patients with metastatic colorectal cancer
Timeline
- Start
- 2020-11-23
- Primary completion
- 2024-03-23
- Completion
- 2024-12-31
Outcome
Outcome not reported
Stopped: “Following the presentation of the SUNLIGHT study results at ASCO GI and the rapid change in patient management in the majority of centers, the IDMC experts recommended halting inclusion in the SOREGATT study with immediate effect.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Regorafenib | Small molecule | 160 mg | — |
| Subject | Trifluridine/Tipiracil | Unknown | 35 mg/m2 | Oral |