drugset / Trial / NCT04452383
f Adding Ketamine to Propofol For Drug-induced Sleep Endoscopy in Adult Patients With Obstructive Sleep Apnea
RandomizedParallel-groupQuadruple-blindSupportive care
Summary
The investigator compared the sedative effects of propofol alone and ketamine added to propofol in drug induced sleep endoscopy
Timeline
- Start
- 2020-07-23
- Primary completion
- 2021-12-30
- Completion
- 2021-12-30
Publications
- Background Cho JS, Soh S, Kim EJ, Cho HJ, Shin S, Kim HJ, Koo BN. Comparison of three sedation regimens for drug-induced sleep endoscopy. Sleep Breath. 2015 May;19(2):711-7. doi: 10.1007/s11325-015-1127-9. Epub 2015 Feb 3.
- Background De Vito A, Agnoletti V, Berrettini S, Piraccini E, Criscuolo A, Corso R, Campanini A, Gambale G, Vicini C. Drug-induced sleep endoscopy: conventional versus target controlled infusion techniques--a randomized controlled study. Eur Arch Otorhinolaryngol. 2011 Mar;268(3):457-62. doi: 10.1007/s00405-010-1376-y. Epub 2010 Sep 2.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Ketamine | Small molecule | — | Intravenous |
| Comparator | Propofol | Small molecule | — | Intravenous |