drugset / Trial / NCT04454281
Topical Naloxone to Diagnose Ocular Pain
RandomizedCrossoverTriple-blindDiagnostic
Summary
Chronic ocular neuropathic pain may be misdiagnosed as dry eye disease. Our study aims to identify a population with previous monocular trauma and dry eye symptoms and differentiate neuropathic from dry eye pain using topical corneal naloxone hydrochloride.
Timeline
- Start
- 2020-10-01
- Primary completion
- 2020-12-03
- Completion
- 2020-12-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Naloxone | Small molecule | 0.02 mg | Topical |
| Subject | Naloxone | Small molecule | 0.08 mg | Topical |