drugset / Trial / NCT04456387

An Open Label Study to Determine the Safety and Efficacy of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection in Adolescent and Adult Patients With Hemophilia A.

NCT04456387

Phase 3 Completed 119 enrolled Zhengzhou Gensciences Inc
Non-randomizedParallel-groupOpen-labelTreatment

Summary

The primary objectives of the study are to evaluate the efficacy of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection (FRSW107) in the Prevention and Treatment of Bleeding in patients with hemophilia A. The secondary objectives are to evaluate the efficacy and safety of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection (FRSW107) in the prevention and treatment of bleeding episodes, to investigate the quality of life in patients who used the FRSW107.

Timeline

Start
2020-10-15
Primary completion
2021-09-30
Completion
2021-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject FRSW107 Protein / enzyme biologic 30 iu/kg
Subject FRSW107 Protein / enzyme biologic 50 iu/kg

Indications