drugset / Trial / NCT04456816

A Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of Treatment With AP1189 in Patients With iMN and Severe Proteinuria

NCT04456816 ↗

Phase 2 Recruiting 23 enrolled SynAct Pharma Aps
RandomizedParallel-groupTriple-blindTreatment

Summary

This study is an exploratory, randomized, double-blind, multicenter, placebo-controlled study with repeated doses of AP1189. The study population will consist of patients with idiopathic membranous nephropathy (iMN) and severe proteinuria who are on ACE inhibitor or angiotensin II receptor blocker treatment.

Timeline

Start
2020-08-31
Primary completion
2026-06-30
Completion
2026-06-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Resomelagon Small molecule 100 mg —