drugset / Trial / NCT04459338
A Dose-response Study Examining the Contribution of GLP-1 Receptor Signaling to Glucagon-stimulated Insulin Secretion
Phase 3
Completed
11 enrolled
Adrian Vella
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · collab
RandomizedCrossoverOpen-labelBasic science
Summary
The GLP-1 receptor (GLP1R) gene is found on the beta cells of the pancreas. Its role is in the control of blood sugar level by enhancing insulin secretion from the pancreas after eating a meal. The purpose of this research study is to evaluate the role of GLP1R in the response to elevated glucagon concentrations.
Timeline
- Start
- 2021-03-04
- Primary completion
- 2022-06-14
- Completion
- 2022-06-14
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Avexitide | Peptide | — | — |
Indications
No indication recorded.