High Resolution, 18F-PSMA PET-MRI Before Prostate Cancer HIFU or Radical Prostatectomy

Phase 2 Completed 62 enrolled Alessandro D'Agnolo Progenics Pharmaceuticals, Inc. · collab

Non-randomizedParallel-groupOpen-labelOther

Summary

This prospective trial aims to determine if enhanced prostate imaging using two novel imaging technologies (high resolution DWI and 18F-PSMA PET-MRI) will detect prostate cancers not seen on standard multiparametric prostate MRI in patients considered candidates for focal HIFU.

Timeline

Start: 2021-04-06
Primary completion: 2024-09-03
Completion: 2024-09-03

Publications

Basso Dias A, Ghai S, Ortega C, Mirshahvalad SA, Perlis N, Berlin A, Avery L, Veit-Haibach P, van der Kwast T, Metser U. Impact of 18F-DCFPyL PET/MRI in Selecting Men With Low-/Intermediate-Risk Prostate Cancer for Focal Ablative Therapies. Clin Nucl Med. 2023 Oct 1;48(10):e462-e467. doi: 10.1097/RLU.0000000000004819.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	18F-PSMA	Diagnostic / imaging agent	370 mbq	—

High Resolution, 18F-PSMA PET-MRI Before Prostate Cancer HIFU or Radical Prostatectomy

Summary

Timeline

Publications

Drugs

Indications