Early Sequential Nephron Blockade in Acute Heart Failure Patients: A Randomised, Controlled Study

Summary

This study aims to demonstrate the efficacy of sequential nephron blockade by adding hydrochlorothiazide or spironolactone on intravenous furosemide compared to intravenous furosemide alone in the treatments of volume overload in patients with acute heart failure who have diuretic resistance from furosemide stress test.

Timeline

Start

2020-08-13

Primary completion

2022-07-31

Completion

2022-12-31

Drugs

Indications