Low Versus High Corticosteroid Use in Ventilator Associated Pneumonia

Summary

patients who had \>3 on Murray score and \>6 on CPIS allocated randomly in two groups 120 patients in each. Group A received 30 mg/kg methyl-prednisolone slowly intravenous in 250 mL normal saline every 8 hours for only 48 hours while group B received 1 mg/kg/day methyl-prednisolone divided to three doses given every 8 hours for two weeks. Duration of the study last 16 days, Morbidity considered if no improvement in any or all clinical parameters of both Murray and CPIS scores and failure of weaning of patients from the ventilator at the studied period.

Timeline

Start

2018-01-02

Primary completion

2020-02-14

Completion

2020-02-25

Drugs

Indications

No indication recorded.