drugset / Trial / NCT04474002
Efficacy, Tolerance and Safety of Split Dose Bowel Preparation for Colonoscopy: 4L Polyethylene Glycol (PEG) Versus 1L Polyethylene Glycol Plus Sodium Picosulfate-magnesium Citrate (SPMC)
RandomizedParallel-groupDouble-blindTreatment
Summary
4L split dose PEG is the gold standard for bowel preparation, however it comes with poor tolerability and poor compliance. Combination of PEG with different agent is useful in reducing total volume, improving compliance and tolerance of patient. The objective of this study is to demonstrate that combination bowel preparation, PEG plus SPMC solution, has similar efficacy and safety profile whereas with a better tolerance when compared to large volume PEG.
Timeline
- Start
- 2020-12-07
- Primary completion
- 2022-12-31
- Completion
- 2022-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Klean-Prep® | Other / unclassified | 1000 ml | — |
| Comparator | Klean-Prep® | Other / unclassified | 4000 ml | — |
| Subject | PICOPREP | Small molecule | 2 unknown | — |
Indications
No indication recorded.