drugset / Trial / NCT04474314

A Study of IMR-687 in Subjects With Sickle Cell Disease

NCT04474314 ↗

Phase 2 Terminated 115 enrolled Cardurion Pharmaceuticals, Inc. Imara, Inc. · collab
RandomizedParallel-groupTriple-blindTreatment

Summary

A Study to Evaluate the Safety and Efficacy of IMR-687 in Subjects with Sickle Cell Disease

Timeline

Start
2020-08-13
Primary completion
2022-03-02
Completion
2022-05-04

Outcome

Outcome not reported

Stopped: “A recently conducted Interim analysis of IMR-SCD-301 demonstrated that while IMR-687 was generally well-tolerated, it failed to meet its primary efficacy endpoint. So, the sponsor has decided to discontinue this study.”

Drugs

EvaluationDrugModalityDoseRoute
Subject Tovinontrine Small molecule — Oral

Indications