drugset / Trial / NCT04479891
Effect of Itraconazole on the Pharmacokinetics of Pyrotinib in Healthy Subjects
NaSingle-groupOpen-labelBasic science
Summary
The study will assess the effect of multiple oral doses of itraconazole on the single dose pharmacokinetic parameters of pyrotinib in healthy Chinese subjects. The safety of pyrotinib alone and when co-administered with itraconazole will also be assessed.
Timeline
- Start
- 2019-09-18
- Primary completion
- 2019-10-11
- Completion
- 2019-11-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Itraconazole | Small molecule | 200 mg | Oral |
| Subject | Pyrotinib | Small molecule | — | Oral |
Indications
No indication recorded.