drugset / Trial / NCT04481932

Trastuzumab Combined With Pyrrolidine and Chemotherapy for Locally HER2 Positive Breast Cancer

NCT04481932 ↗

Phase 2 Recruiting 104 enrolled Peking University
NaSingle-groupOpen-labelTreatment

Summary

This study is a one-arm, open, phase II clinical study, and the study subjects are locally advanced and inflammatoryPatients with sexual or early HER2-positive breast cancer entered the trial period after signing informed consentTo evaluate trastuzumab combined with pyrrolitinib and chemotherapy regimen (TCbH+Py) for HER2 positive breastPathologic complete response rate (pCR) for adenocarcinoma.

Timeline

Start
2020-07
Primary completion
2022-06
Completion
2026-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Pyrotinib Small molecule — —
Subject Trastuzumab Monoclonal antibody — —