drugset / Trial / NCT04482933
HSV G207 With a Single Radiation Dose in Children With Recurrent High-Grade Glioma
Phase 2
Withdrawn
Pediatric Brain Tumor Consortium
American Lebanese Syrian Associated Charities · collabNational Cancer Institute (NCI) · collabTreovir, Inc · collab
NaSingle-groupOpen-labelTreatment
Summary
This study is a clinical trial to assess the efficacy and confirm the safety of intratumoral inoculation of G207 (an experimental virus therapy) combined with a single 5 Gy dose of radiation in recurrent/progressive pediatric high-grade gliomas
Timeline
- Start
- 2025-09-01
- Primary completion
- 2025-12-18
- Completion
- 2025-12-18
Outcome
Outcome not reported
Stopped (Enrollment): “The PBTC lost federal funding and will cease operations in March 2026.PBTC-061 was permanently closed on 10/24/2025 with no patients enrolled.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | G207 | Other / unclassified | 1e+08 unknown | Other |