drugset / Trial / NCT04483167
Clinical Transfer of a Vulnerable Atherosclerotic Plaque Tracer : 99mTc-cAbVCAM1-5 (ATHENA)
NaSingle-groupOpen-labelDiagnostic
Summary
Clinical Transfer of a Tracer of the Vulnerable Atheroma Plate: 99mTc-cAbVCAM1-5. (ATHENA). This is a phase I/IIa, prospective, monocentric, non-controlled, non-randomized, open-label, interventional study.
Timeline
- Start
- 2020-09-15
- Primary completion
- 2023-05
- Completion
- 2023-05
Publications
- Background GBD 2016 Causes of Death Collaborators. Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet. 2017 Sep 16;390(10100):1151-1210. doi: 10.1016/S0140-6736(17)32152-9.
- Background Little WC, Constantinescu M, Applegate RJ, Kutcher MA, Burrows MT, Kahl FR, Santamore WP. Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease? Circulation. 1988 Nov;78(5 Pt 1):1157-66. doi: 10.1161/01.cir.78.5.1157.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | 99mTccAbVCAM1-5 | Diagnostic / imaging agent | 370 mbq | Intravenous |
| Subject | 99mTccAbVCAM1-5 | Diagnostic / imaging agent | 550 mbq | Intravenous |
| Subject | 99mTccAbVCAM1-5 | Diagnostic / imaging agent | 750 mbq | Intravenous |