drugset / Trial / NCT04483440
Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia
Non-randomizedSequentialOpen-labelTreatment
Summary
This study will evaluate safety, tolerability, and preliminary efficacy of a single intravitreal (IVT) injection of a recombinant adeno-associated virus (AAV) gene therapy, 4D-110, in male patients with genetically-confirmed Choroideremia (CHM).
Timeline
- Start
- 2020-06-02
- Primary completion
- 2027-05-26
- Completion
- 2027-08-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | 4D-110 | Gene therapy (AAV / viral vector) | — | Intravitreal |