drugset / Trial / NCT04487093
Clinical Study of Neoantigen Vaccine Combined With Targeted Drugs in the Treatment of Non-small Cell Lung Cancer
Phase 1
Unknown
20 enrolled
First Hospital of Shijiazhuang City
Tianjin Hengjia Biotechnology Development co., LTD · collab
Non-randomizedParallel-groupOpen-labelTreatment
Summary
Neoantigen vaccine is a new field of research in tumor immunotherapy, and some studies have been conducted with success on Melanoma and glioblastoma. Nearly 80% of lung cancers are diagnosed in an advanced stage (IIIB, and IV) and EGFR mutant non-small cell lung cancer will be resistant after targeted drug treatment. Neoantigen vaccine is a new treatment method for lung cancer, especially for patients with drug resistance.
Timeline
- Start
- 2020-05-17
- Primary completion
- 2022-05-17
- Completion
- 2022-12-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | NeoVax | Vaccine | 200 ug | Subcutaneous |