drugset / Trial / NCT04487093

Clinical Study of Neoantigen Vaccine Combined With Targeted Drugs in the Treatment of Non-small Cell Lung Cancer

NCT04487093

Non-randomizedParallel-groupOpen-labelTreatment

Summary

Neoantigen vaccine is a new field of research in tumor immunotherapy, and some studies have been conducted with success on Melanoma and glioblastoma. Nearly 80% of lung cancers are diagnosed in an advanced stage (IIIB, and IV) and EGFR mutant non-small cell lung cancer will be resistant after targeted drug treatment. Neoantigen vaccine is a new treatment method for lung cancer, especially for patients with drug resistance.

Timeline

Start
2020-05-17
Primary completion
2022-05-17
Completion
2022-12-01

Drugs

EvaluationDrugModalityDoseRoute
Subject NeoVax Vaccine 200 ug Subcutaneous